As in past centuries, Christians still speak frequently about the need for sanctification, yet no mutually agreed upon description of sanctification has emerged. The present discussion has chosen to describe the term in relation to what the Bible says about “fruit.” “Fruit” is used widely in the Bible from Genesis to Revelation, referring to edible products from the ground as well as human offspring. In both the OT and the NT the word is used metaphorically to depict human actions. Other terms related to fruit also take on metaphorical meanings to speak of human behavior. Romans 6:22 and 7:4 link such terminology with the sanctification of believers. The contexts of these verses confirm a close tie between fruit and both past sanctification and the present lives of Christians in their progress toward Christlikeness. Galatians 5:22-23 relate the Holy Spirit’s role in producing the present sanctification of believers.