Bible interpreters debate the identity of the little horn in Daniel 8. They even disagree on which verses in Daniel 8 pertain to the little horn. This article determines the pertinent verses by means of a structural and lexical analysis. It then compares the little horn to three primary candidates: Antiochus IV Epiphanes, Rome, and the antichrist. In light of the comparative analysis, the author evaluates the candidates in order to arrive at a conclusion concerning the little horn’s identity.